#Stem cell treatment for spinal cord injury download
If you want more information on how you could bank your children’s baby teeth for potential future therapeutic use, have a chat to one of our team or download our guide to stem cell banking.įor more information on the latest breakthroughs in stem cell therapies and treatments see our news articles.The treatment uses the patient's own stem cells to prevent (further) loss of function after sustaining TSCI, to potentially limit loss of mobility and independence of otherwise life-long impairment. Stem cells are characterized by self-renewal and their ability to become any cell in an organism and promising results have been obtained in experimental models of SCI.Īs with much of the work in stem cells therapy extensive research and clinical trials continue to take place to find safe and efficacious methods of treatment for future generations. However, evidence is building that the transplantation of stem cells or progenitors may support spinal cord repair. There is currently no treatment available that restores the injury-induced loss of function.
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These types of injury result in loss of nervous tissue and consequently loss of motor and sensory function. This ability to prevent scarring could promote anti-aging properties by keeping muscles healthy and functional and could also benefit patients with muscle wasting diseases like muscular dystrophy.Īt the same time stem cell therapy is rapidly evolving and promising treatment for spinal-cord injuries (SCI). However, breakthroughs in stem cell research have demonstrated the potential for stem cells to reduce fibrosis.Ī recent study from the Stanford University School of Medicine has discovered that stem cells in muscle tissue “police themselves” to reduce fibrosis or the build up of scar tissue. The most common sites of injury are the cervical and thoracic areas.ĭespite the ability of muscle fibres to regenerate, muscle function is often compromised after injury due to the formation of dense fibrotic scar tissue.
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A traumatic injury to the spine can cause a bruise, a partial tear, or a complete tear in the spinal cord. It consists of nerves, carrying messages between the brain and the rest of the body. The spinal cord is a long, tube-like structure that begins at the end of the brain stem and continues down to almost the bottom of the spine. In terms of the function of skeletal muscle in the human body, it produces movement, stabilises joints and generates heat. As a result, muscular injuries of this nature are extremely common amongst athletes. These kinds of muscles are under voluntary control, meaning you consciously control what they do. Skeletal muscles cover the entire skeleton, giving your body it’s shape. A skeletal muscle refers to multiple bundles of cells called muscle fibres, and these fibres are surrounded by connective tissue layers. Skeletal muscle is one of three major muscle types, the other two are cardiac muscle and smooth muscle. Whilst Stem Cell therapy has made great strides in a number of areas, including diabetes, stroke, autism and Parkinson’s it remains in its infancy with regard to skeletal muscle and spinal cord injuries and conditions. Skeletal muscle is the most abundant tissue of the human body, it is highly dynamic and has the ability to regenerate, but loss of skeletal muscle through trauma, tumour ablation, or prolonged denervation is a common clinical challenge. Source: Back Up Trust, World Health Organisation Spinal cord injury is associated with a risk of developing secondary conditions that can be debilitating People with a spinal cord injury are two to five times more likely to die prematurely than people without a spinal cord injury
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Studies report male-to-female ratios of up to 4:1 There are 1,000 new cases of SCI every year in the UK Stem Cell Therapy for Skeletal Muscle and Spinal Cord InjuryĤ0,000 people in the UK are living with a Spinal Cord Injury (SCI)